Radiotherapy-exposed CD8(+) and CD4(+) neoantigens enhance tumor control

Lhuillier, C; Rudqvist, NP; Yamazaki, T; Zhang, T; Charpentier, M; Galluzzi, L; Dephoure, N; Clement, CC; Santambrogio, L; Zhou, XK; Formenti, SC; Demaria, S

Demaria, S (corresponding author), Weill Cornell Med, Dept Radiat Oncol, 1300 York Ave,Rm E-215D,Box 169, New York, NY 10065 USA.

JOURNAL OF CLINICAL INVESTIGATION, 2021; 131 (5):

Abstract

Neoantigens generated by somatic nonsynonymous mutations are keytargets of tumor-specific T cells, but only a small number of mutations predicted to b......

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