Disruption of OCT4 Ubiquitination Increases OCT4 Protein Stability and ASH2L-B-Mediated H3K4 Methylation Promoting Pluripotency Acquisition

Li, S; Xiao, F; Zhang, JM; Sun, XZ; Wang, H; Zeng, YW; Hu, J; Tang, F; Gu, JJ; Zhao, YM; Jin, Y; Liao, B

Jin, Y; Liao, B (reprint author), Shanghai Jiao Tong Univ, Dept Histol Genet & Dev Biol, Shanghai Key Lab Reprod Med, Basic Clin Res Ctr,Renji Hosp,Sch Med, 227 South Chongqing Rd, Shanghai 200025, Peoples R China.; Jin, Y (reprint author), Chinese Acad S

STEM CELL REPORTS, 2018; 11 (4): 973

Abstract

The protein level of OCT4, a core pluripotency transcription factor, is vital for embryonic stem cell (ESC) maintenance, differentiation, and somatic ......

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