Genome-Scale CRISPR screen identifies LAPTM5 driving lenvatinib resistance in hepatocellular carcinoma

Pan, JM; Zhang, M; Dong, LQ; Ji, SY; Zhang, J; Zhang, S; Lin, YP; Wang, XY; Ding, ZB; Qiu, SJ; Gao, DM; Zhou, J; Fan, J; Gao, Q

Fan, J; Gao, Q (通讯作者)，Fudan Univ, Liver Canc Inst, Dept Liver Surg & Transplantat, Zhongshan Hosp, 180 Fenglin Rd, Shanghai 200032, Peoples R China.

AUTOPHAGY, 2023; 19 (4): 1184

Abstract

Drug resistance has greatly limited the clinical efficacy of lenvatinib in hepatocellular carcinoma (HCC). However, the underlying molecular mechanism......

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