Novel glucagon- and OXM-based peptides acting through glucagon and GLP-1 receptors with body weight reduction and anti-diabetic properties

Cai, XG; Li, CY; Zhou, J; Dai, YX; Avraham, Y; Sun, LD; Liu, CX; Tong, JY; Wang, Y; Bi, XZ; He, L; Huang, WL; Qian, H

Qian, H (corresponding author), China Pharmaceut Univ, State Key Lab Nat Med, Ctr Drug Discovery, 24 Tongjiaxiang, Nanjing 210009, Peoples R China.

BIOORGANIC CHEMISTRY, 2020; 95 ():

Abstract

Oxyntomodulin (OXM) is an endogenous gastrointestinal hormone, which activates both the Glucagon-like peptide-1 receptor (GLP-1R) and the glucagon rec......

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