Arctigenin mitigates insulin resistance by modulating the IRS2/GLUT4 pathway via TLR4 in type 2 diabetes mellitus mice

Zhou, YY; Liu, LN; Xiang, RX; Bu, XY; Qin, GZ; Dai, JJ; Zhao, ZG; Fang, X; Yang, S; Han, J; Wang, GD

Han, J; Wang, GD (通讯作者)，Wannan Med Coll, Drug Res & Dev Ctr, Sch Pharm, Wuhu 241002, Anhui, Peoples R China.;Han, J; Wang, GD (通讯作者)，Anhui Prov Key Lab Act Biol Macromol, Anhui Prov Engn Lab Screening & Re Evaluat Act Cp, Anhui Prov Engn Res Ctr Polysaccharide Drugs, Wuhu 241002, Peoples R China.

INTERNATIONAL IMMUNOPHARMACOLOGY, 2023; 114 ():

Abstract

Arctigenin (AR), extracted from Arctium lappa L. (Burdock), is a folk herbal medicine used to treat diabetes. However, its mechanism of action has rem......

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