Targeting Tn-positive tumors with an afucosylated recombinant anti-Tn IgG

Matsumoto, Y; Jia, N; Heimburg-Molinaro, J; Cummings, RD

Cummings, RD (通讯作者),Harvard Med Sch, Beth Israel Deaconess Med Ctr, Dept Surg, 3 Blackfan Circle,CLS 11090, Boston, MA 02115 USA.;Cummings, RD (通讯作者),Beth Israel Deaconess Med Ctr, Dept Surg, Surg Sci, CLS 11087,3 Blackfan Circle, Boston, MA 02115 USA.

SCIENTIFIC REPORTS, 2023; 13 (1):

Abstract

The aberrant expression of the Tn antigen (CD175) on surface glycoproteins of human carcinomas is associated with tumorigenesis, metastasis, and poor ......

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