Bcl-xL inhibits PINK1/Parkin-dependent mitophagy by preventing mitochondrial Parkin accumulation

Yu, S; Du, MY; Yin, A; Mai, ZH; Wang, Y; Zhao, MX; Wang, XP; Chen, TS

Chen, TS (corresponding author), South China Normal Univ, Coll Biophoton, MOE Key Lab Laser Life Sci, Guangzhou 510631, Peoples R China.; Chen, TS (corresponding author), South China Normal Univ, Coll Biophoton, Guangdong Prov Key Lab Laser Life Sci, Guangzhou 510631, Peoples R China.; Wang, XP (corresponding author), Jinan Univ, Affiliated Hosp 1, Dept Pain Management, Guangzhou 510632, Peoples R China.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2020; 122 ():

Abstract

This report aims to explore how Bcl-xL, a Bcl-2 family protein, regulates PINK1/Parkin-dependent mitophagy. Compared with the Hela cells expressing Pa......

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