A possible link to uracil DNA glycosylase in the synergistic action of HDAC inhibitors and thymidylate synthase inhibitors

Showler, MS; Weiser, BP

Weiser, BP (corresponding author), Rowan Univ, Sch Osteopath Med, Dept Mol Biol, Stratford, NJ 08084 USA.

JOURNAL OF TRANSLATIONAL MEDICINE, 2020; 18 (1):

Abstract

It is well established that thymidylate synthase inhibitors can cause cellular toxicity through uracil DNA glycosylase (UNG2)-dependent pathways. Addi......

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