Formal asymmetric synthesis of (+)-tofacitinib

Liao, HC; Uang, BJ

Uang, BJ (reprint author), Natl Tsing Hua Univ, Dept Chem, 101,Sec 2,Kuang Fu Rd, Hsinchu 30013, Taiwan.

TETRAHEDRON-ASYMMETRY, 2017; 28 (1): 105

Abstract

Tofacitinib is an efficient and selective Janus kinase 3 (JAK3) inhibitor, and is used as an immunosuppressant drug for the treatment of rheumatoid ar......

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