Novel p-carborane-containing multitarget anticancer agents inspired by the metabolism of 17 beta-estradiol

Kaise, A; Ohta, K; Endo, Y

Ohta, K (reprint author), Tohoku Med & Pharmaceut Univ, Fac Pharmaceut Sci, Aoba Ku, 4-4-1 Komatsushima, Sendai, Miyagi 9818558, Japan.

BIOORGANIC & MEDICINAL CHEMISTRY, 2017; 25 (24): 6371

Abstract

The female hormone 17 beta-estradiol (E2) is synthesized from estrone by steroid sulfatase (STS), and metabolized into 2-methoxyestradiol (2-ME), wher......

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