Covalent fragment inhibits intramembrane proteolysis

Eden, A; Zhao, J; Xiao, YY; Gibson, J; Wang, CY

Wang, CY (通讯作者),Ctr Biotechnol & Interdisciplinary Studies, Troy, NY 12180 USA.;Wang, CY (通讯作者),Dept Chem & Chem Biol, Troy, NY 12180 USA.;Wang, CY (通讯作者),Dept Biol Sci, Troy, NY 12180 USA.

FRONTIERS IN MOLECULAR BIOSCIENCES, 2022; 9 ():

Abstract

Alzheimer's disease (AD) is a serious public health crisis with only one current modifying treatment. The reduction of amyloid load by targeting gamma......

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