Redox priming promotes Aurora A activation during mitosis

Lim, DC; Joukov, V; Rettenmaier, TJ; Kumagai, A; Dunphy, WG; Wells, JA; Yaffe, MB

Lim, DC; Yaffe, MB (corresponding author), MIT, MIT Ctr Precis Canc Med, Koch Inst Integrat Canc Res, 77 Massachusetts Ave, Cambridge, MA 02139 USA.; Lim, DC; Yaffe, MB (corresponding author), MIT, Dept Biol Engn, 77 Massachusetts Ave, Cambridge, MA 02139 USA.; Lim, DC; Yaffe, MB (corresponding author), MIT, Dept Biol, 77 Massachusetts Ave, Cambridge, MA 02139 USA.; Yaffe, MB (corresponding author), Harvard Med Sch, Beth Israel Deaconess Med Ctr, Div Acute Care Surg Trauma & Surg Crit Care, Boston, MA 02215 USA.; Yaffe, MB (corresponding author), Harvard Med Sch, Beth Israel Deaconess Med Ctr, Div Surg Oncol, Boston, MA 02215 USA.

SCIENCE SIGNALING, 2020; 13 (641):

Abstract

Cell cycle-dependent redox changes can mediate transient covalent modifications of cysteine thiols to modulate the activities of regulatory kinases an......

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