Cyclooxygenase-derived proangiogenic metabolites of epoxyeicosatrienoic acids

Rand, AA; Barnych, B; Morisseau, C; Cajka, T; Lee, KSS; Panigrahy, D; Hammock, BD

Hammock, BD (reprint author), Univ Calif Davis, Dept Entomol & Nematol, Davis, CA 95616 USA.; Hammock, BD (reprint author), Univ Calif Davis, UC Davis Comprehens Canc Ctr, Davis, CA 95616 USA.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017; 114 (17): 4370

Abstract

Arachidonic acid (ARA) is metabolized by cyclooxygenase (COX) and cytochrome P450 to produce proangiogenic metabolites. Specifically, epoxyeicosatrien......

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