IMPDH2 promotes colorectal cancer progression through activation of the PI3K/AKT/mTOR and PI3K/AKT/FOXO1 signaling pathways

Duan, SY; Huang, WQ; Liu, XT; Liu, XM; Chen, NN; Xu, Q; Hu, YK; Song, W; Zhou, J

Zhou, J (reprint author), Southern Med Univ, Nanfang Hosp, Dept Pathol, 1838 Guangzhou North Rd, Guangzhou 510515, Guangdong, Peoples R China.; Zhou, J (reprint author), Southern Med Univ, Sch Basic Med Sci, Dept Pathol, 1838 Guangzhou North Rd, Guangzhou

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2018; 37 ():

Abstract

Background: Inosine 5'-monophosphate dehydrogenase type II (IMPDH2) was originally identified as an oncogene in several human cancers. However, the cl......

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