Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1

Sizemore, GM; Balakrishnan, S; Hammer, AM; Thies, KA; Trimboli, AJ; Wallace, JA; Sizemore, ST; Kladney, RD; Woelke, SA; Yu, L; Fernandez, SA; Chakravarti, A; Leone, G; Ostrowski, MC

Sizemore, GM; Ostrowski, MC (reprint author), Ohio State Univ, Dept Canc Biol & Genet, Comprehens Canc, 570A Biomed Res Tower,460W 12th Ave, Columbus, OH 43210 USA.

ONCOGENE, 2017; 36 (16): 2297

Abstract

Fibroblasts within the mammary tumor microenvironment are active participants in carcinogenesis mediating both tumor initiation and progression. Our g......

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