PBPK modeling-based optimization of site-specific chemo-photodynamic therapy with far-red light-activatable paclitaxel prodrug

Li, MJ; Nguyen, L; Subramaniyan, B; Bio, M; Peer, CJ; Kindrick, J; Figg, WD; Woo, S; You, Y

Woo, S; You, Y (reprint author), Univ Oklahoma, Coll Pharm, Dept Pharmaceut Sci, Hlth Sci Ctr, 1110 N Stonewall Ave CPB 317, Oklahoma City, OK 73117 USA.

JOURNAL OF CONTROLLED RELEASE, 2019; 308 (): 86

Abstract

Photodynamic therapy (PDT) is a clinically approved therapeutic modality to treat certain types of cancers. However, incomplete ablation of tumor is a......

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