Scientific rationale for a higher dose of nusinersen

Finkel, RS; Ryan, MM; Pascual, SIP; Day, JW; Mercuri, E; De Vivo, DC; Foster, R; Montes, J; Gurgel-Giannetti, J; MacCannell, D; Berger, Z

Berger, Z (通讯作者)，Biogen, 225 Binney St, Cambridge, MA 02142 USA.

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY, 2022; 9 (6): 819

Abstract

Objective: The long-term favorable safety profile of nusinersen provides an opportunity to consider a higher dose. We report on the relationships betw......

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