Upregulated YB-1 protein promotes glioblastoma growth through a YB-1/CCT4/mLST8/mTOR pathway

Wang, JZ; Zhu, H; You, P; Liu, H; Wang, WK; Fan, XJ; Yang, Y; Xu, KR; Zhu, YF; Li, QY; Wu, P; Peng, C; Wong, CCL; Li, KC; Shi, YF; Zhang, N; Wang, XX; Zeng, R; Huang, Y; Yang, LS; Wang, ZF; Hui, JY

Hui, JY (通讯作者),Univ Chinese Acad Sci, Chinese Acad Sci, CAS Ctr Excellence Mol Cell Sci, State Key Lab Mol Biol,Shanghai Inst Biochem & Ce, Shanghai, Peoples R China.;Wang, ZF (通讯作者),Univ Chinese Acad Sci, Chinese Acad Sci, CAS Key Lab Computat Biol, Shanghai Inst Nutr & Hlth, Shanghai, Peoples R China.;Yang, LS (通讯作者),Fudan Univ, Shanghai Med Coll, Huashan Hosp, Dept Neurosurg, Shanghai, Peoples R China.

JOURNAL OF CLINICAL INVESTIGATION, 2022; 132 (8):

Abstract

Y-box-binding protein 1 (YB-1) is a multifunctional RNA binding protein involved in virtually every step of RNA metabolism. However, the functions and......

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