Phosphorylation at tyrosine 317 and 508 are crucial for PIK3CA/p110a to promote CRC tumorigenesis

Wang, T; Sun, LC; Chen, CK; Zhang, YC; He, BY; Zhang, YH; Wang, ZH; Xue, HB; Hao, YJ

Hao, YJ (通讯作者)，Shanghai Jiao Tong Univ, Sch Med, State Key Lab Oncogenes & Related Genes, Shanghai Canc Inst,Renji Hosp, Shanghai 200032, Peoples R China.;Xue, HB (通讯作者)，Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Minist Hlth,Div Gastroenterol & Hepatol,Key Lab Ga, Shanghai 200001, Peoples R China.

CELL AND BIOSCIENCE, 2023; 13 (1):

Abstract

Background PI3K/AKT signaling pathway plays important role in tumorigenesis of human cancer. Protein phosphorylation is crucial for signaling transduc......

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