Multimeric Insulin Desensitizes Insulin-Specific B Cells

Johnson, SN; Griffin, JD; Hulbert, C; DeKosky, BJ; Thomas, JW; Berkland, CJ

Berkland, CJ (corresponding author), Univ Kansas, Dept Pharmaceut Chem, Bioengn Grad Program, Lawrence, KS 66045 USA.; Berkland, CJ (corresponding author), Univ Kansas, Dept Chem & Petr Engn, Lawrence, KS 66045 USA.

ACS APPLIED BIO MATERIALS, 2020; 3 (9): 6319

Abstract

Adaptive immunity plays a central role in the pathogenesis of type 1 diabetes. Among past treatment approaches, B cell ablation has yielded unmistakab......

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