In vivo activity of the dual SYK/FLT3 inhibitor TAK-659 against pediatric acute lymphoblastic leukemia xenografts

Hughes, K; Evans, K; Earley, EJ; Smith, CM; Erickson, SW; Stearns, T; Philip, VM; Neuhauser, SB; Chuang, JH; Jocoy, EL; Bult, CJ; Teicher, BA; Smith, MA; Lock, RB

Lock, RB (通讯作者)，UNSW, Childrens Canc Inst, Lowy Canc Res Ctr, POB 81, Randwick, NSW 2031, Australia.

PEDIATRIC BLOOD & CANCER, 2023; 70 (9):

Abstract

BackgroundWhile children with acute lymphoblastic leukemia (ALL) experience close to a 90% likelihood of cure, the outcome for certain high-risk pedia......

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