Pharmacokinetic assessment of alprazolam-induced neonatal abstinence syndrome using physiologically based pharmacokinetic model

Yamamoto, K; Fukushima, S; Mishima, Y; Hashimoto, M; Yamakawa, K; Fujioka, K; Iijima, K; Yano, I

Yamamoto, K (reprint author), Kobe Univ Hosp, Dept Pharm, Kobe, Hyogo, Japan.

DRUG METABOLISM AND PHARMACOKINETICS, 2019; 34 (6): 400

Abstract

Sustained benzodiazepine use during pregnancy can induce neonatal abstinence syndrome (NAS). In this study, the association between NAS and plasma alp......

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