On the mechanism of substrate/non-substrate recognition by P-glycoprotein

Mukhametov, A; Raevsky, OA

Mukhametov, A (reprint author), Russian Acad Sci, Inst Physiol Act Cpds, Dept Comp Aided Mol Design, Severny Pr D 1, Chernogolovka 142432, Moscow Region, Russia.

JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2017; 71 ( ): 227

Abstract

P-Glycoprotein (P-gp, multi-drug resistance protein, MDR1) plays a gatekeeper role, interfering delivery of multiple pharmaceuticals to the target tis......

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