Mitotic CDK1 and 4E-BP1 II: A single phosphomimetic mutation in 4E-BP1 induces glucose intolerance in mice

Cao, SM; Jurczak, MJ; Shuda, Y; Sun, R; Shuda, M; Chang, Y; Moore, PS

Moore, PS (通讯作者),Univ Pittsburgh, Hillman Canc Ctr, Canc Virol Program, Pittsburgh, PA 15232 USA.

PLOS ONE, 2023; 18 (3):

Abstract

ObjectiveCyclin-dependent kinase 1 (CDK1)/cyclin B1 phosphorylates many of the same substrates as mTORC1 (a key regulator of glucose metabolism), incl......

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