From checkpoint to checkpoint: DNA damage ATR/Chk1 checkpoint signalling elicits PD-L1 immune checkpoint activation

Mouw, KW; Konstantinopoulos, PA

Konstantinopoulos, PA (reprint author), Harvard Med Sch, Dana Farber Canc Inst, Gynecol Med Oncol Program, Boston, MA 02215 USA.

BRITISH JOURNAL OF CANCER, 2018; 118 (7): 933

Abstract

Multiple clinical studies have revealed a link between genomic instability and response to anti-PD-1/PD-L1 therapy in cancer management. A recent stud......

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