Osteoclasts, Master Sculptors of Bone

Veis, DJ; O'Brien, CA

Veis, DJ (通讯作者),Washington Univ, Sch Med, Musculoskeletal Res Ctr, Div Bone & Mineral Dis, St Louis, MO 63110 USA.;Veis, DJ (通讯作者),Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA.;Veis, DJ (通讯作者),Shriners Hosp Children, St Louis, MO 63110 USA.

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE, 2023; 18 (): 257

Abstract

Osteoclasts are multinucleated cells with the unique ability to resorb bone matrix. Excessive production or activation of osteoclasts leads to skeleta......

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