Pairing of single mutations yields obligate Cre-type site-specific recombinases

Hoersten, J; Ruiz-Gomez, G; Lansing, F; Rojo-Romanos, T; Schmitt, LT; Sonntag, J; Pisabarro, MT; Buchholz, F

Buchholz, F (通讯作者)，Tech Univ Dresden, Med Fac, D-01307 Dresden, Germany.;Buchholz, F (通讯作者)，Tech Univ Dresden, Univ Hosp Carl Gustav Carus, UCC Sect Med Syst Biol, D-01307 Dresden, Germany.

NUCLEIC ACIDS RESEARCH, 2022; 50 (2): 1174

Abstract

Tyrosine site-specific recombinases (SSRs) represent a versatile genome editing tool with considerable therapeutic potential. Recent developments to e......

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