Bupivacaine inhibits a small conductance calcium-activated potassium type 2 channel in human embryonic kidney 293 cells

Chen, HF; Jin, ZS; Xia, FF; Fu, ZJ

Fu, ZJ (corresponding author), Shandong Univ, Dept Pain Management, Shandong Prov Hosp, Cheeloo Coll Med, 324 Jingwu Rd, Jinan 250021, Peoples R China.

BMC PHARMACOLOGY & TOXICOLOGY, 2021; 22 (1):

Abstract

Background Bupivacaine blocks many ion channels in the heart muscle, causing severe cardiotoxicity. Small-conductance calcium-activated potassium type......

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