Combined BRAF(V600E) and MEK blockade for BRAF(V600E)-mutant gliomas

Zhang, J; Yao, TW; Hashizume, R; Hariono, S; Barkovich, KJ; Fan, QW; Prados, M; James, CD; Weiss, WA; Nicolaides, T

Nicolaides, T (reprint author), Univ Calif San Francisco, Dept Pediat, 1450 3rd St, San Francisco, CA 94158 USA.; Nicolaides, T (reprint author), Univ Calif San Francisco, Dept Neurol Surg, 1450 3rd St,HD400, San Francisco, CA 94158 USA.

JOURNAL OF NEURO-ONCOLOGY, 2017; 131 (3): 495

Abstract

BRAF(V600E) is a common finding in glioma (about 10-60% depending on histopathologic subclassification). BRAF(V600E) monotherapy shows modest preclini......

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