Regulation of p27 (Kip1) by Ubiquitin E3 Ligase RNF6

Deshmukh, D; Xu, J; Yang, X; Shimelis, H; Fang, SY; Qiu, Y

Qiu, Y (通讯作者)，Univ Maryland, Dept Pharmacol, Sch Med, Baltimore, MD 21201 USA.;Qiu, Y (通讯作者)，Vet Affairs Med Ctr, 10 North Greene St,Suite 3D-150, Baltimore, MD 21201 USA.

PHARMACEUTICS, 2022; 14 (4):

Abstract

The cyclin-dependent kinase inhibitor p27 (Kip1) is an important regulator of the G1/S checkpoint. It is degraded by the SCF-SKP2 complex in late G1 t......

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