Sennoside A is a novel inhibitor targeting caspase-1

Wu, JS; Lan, YJ; Shi, XK; Huang, WG; Li, S; Zhang, JZ; Wang, H; Wang, F; Meng, XL

Meng, XL (通讯作者)，Chengdu Univ Tradit Chinese Med, Innovat Inst Chinese Med & Pharm, State Key Lab Southwestern Chinese Med Resources, Chengdu 611130, Peoples R China.;Wang, F (通讯作者)，Chinese Acad Sci, Chengdu Inst Biol, Key Lab Nat Med & Clin Translat, Chengdu 610041, Peoples R China.

FOOD & FUNCTION, 2022; 13 (19): 9782

Abstract

The assembly of inflammasomes drives caspase-1 activation, which further promotes proinflammatory cytokine secretion and downstream pyroptosis. The di......

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