CDKL5 deficiency in forebrain glutamatergic neurons results in recurrent spontaneous seizures

Wang, HT; Zhu, ZA; Li, YY; Lou, SS; Yang, G; Feng, X; Xu, W; Huang, ZL; Cheng, XW; Xiong, ZQ

Xiong, ZQ (corresponding author), Chinese Acad Sci, Inst Neurosci, CAS Ctr Excellence Brain Sci & Intelligence Techn, State Key Lab Neurosci, 320 Yueyang Rd, Shanghai 200031, Peoples R China.

EPILEPSIA, 2021; 62 (2): 517

Abstract

Objective Mutations of the cyclin-dependent kinase-like 5 (CDKL5) gene cause severe neurodevelopmental disorders characterized by intractable epilepsy......

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