Epicutaneous vaccination with protease inhibitor-treated papain prevents papain-induced Th2-mediated airway inflammation without inducing Th17 in mice

Kunimine, S; Takai, T; Kamijo, S; Maruyama, N; Kimitsu, T; Masutani, Y; Yoshimura, T; Suchiva, P; Shimizu, S; Ogawa, H; Okumura, K; Ikeda, S

Takai, T (corresponding author), Juntendo Univ, Grad Sch Med, Atopy Allergy Res Ctr, Bunkyo Ku, 2-1-1 Hongo, Tokyo 113, Japan.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021; 546 (): 192

Abstract

Environmental allergen sources such as house dust mites contain proteases, which are frequently al lergens themselves. Inhalation with the exogenous p......

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