Impact of Acetylated and Non-Acetylated Fucose Analogues on IgG Glycosylation

Zimmermann, M; Ehret, J; Kolmar, H; Zimmer, A

Zimmermann, M (reprint author), Merck Life Sci, Upstream R&D, Frankfurter Str 250, D-64293 Darmstadt, Germany.; Zimmermann, M (reprint author), Tech Univ Darmstadt, Inst Organ Chem & Biochem, Alarich Weiss Str 4, D-64287 Darmstadt, Germany.

ANTIBODIES, 2019; 8 (1):

Abstract

The biological activity of therapeutic antibodies is highly influenced by their glycosylation profile. A valuable method for increasing the cytotoxic ......

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