Biological and clinical insights from a randomized phase 2 study of an anti-oncostatin M monoclonal antibody in systemic sclerosis

Denton, CP; Del Galdo, F; Khanna, D; Vonk, MC; Chung, L; Johnson, SR; Varga, J; Furst, DE; Temple, J; Zecchin, C; Csomor, E; Lee, A; Wisniacki, N; Flint, SM; Reid, J

Denton, CP (通讯作者),UCL, Ctr Rheumatol & Connect Tissue Dis, Div Med, Rowland Hill St, London NW3 2PF, England.

RHEUMATOLOGY, 2022; 62 (1): 234

Abstract

Objectives The cytokine oncostatin M (OSM) is implicated in the pathology of SSc. Inhibiting OSM signalling using GSK2330811 (an anti-OSM monoclonal a......

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