Macrocyclic factor XIa inhibitors

Wang, CL; Corte, JR; Rossi, KA; Bozarth, JM; Wu, YM; Sheriff, S; Myers, JE; Luettgen, JM; Seiffert, DA; Wexler, RR; Quan, ML

Quan, ML (reprint author), Bristol Myers Squibb Co, Res & Dev, 350 Carter Rd, Hopewell, NJ 08540 USA.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017; 27 (17): 4056

Abstract

A series of macrocyclic factor XIa (FXIa) inhibitors was designed based on an analysis of the crystal structures of the acyclic phenylimidazole compou......

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