Prospecting for molecular glues

den Besten, W; Lipford, JR

Lipford, JR (corresponding author), Amgen Res, Dept Oncol Res, Thousand Oaks, CA 91320 USA.

NATURE CHEMICAL BIOLOGY, 2020; 16 (11): 1157

Abstract

Two recent studies identified CDK12 inhibitors that bind to CDK12-cyclin K complexes and act as molecular glues to stabilize an interaction with the u......

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