PXR mediates mifepristone-induced hepatomegaly in mice

Yao, XP; Jiao, TY; Jiang, YM; Fan, SC; Zhao, YY; Yang, X; Gao, Y; Li, F; Zhou, YY; Chen, PP; Huang, M; Bi, HC

Bi, HC (corresponding author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Design & Evaluat, Guangzhou 510006, Peoples R China.; Bi, HC (corresponding author), Southern Med Univ, Sch Pharm, Guangzhou 510515, Peoples R China.

ACTA PHARMACOLOGICA SINICA, ; ():

Abstract

Mifepristone (Mif), an effective synthetic steroidal antiprogesterone drug, is widely used for medical abortion and pregnancy prevention. Due to its a......

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