Population Pharmacokinetic-Pharmacodynamic Model of Serum Transthyretin Following Patisiran Administration

Goel, V; Gosselin, NH; Jomphe, C; Zhang, XP; Marier, JF; Robbie, GJ

Goel, V (corresponding author), Alnylam Pharmaceut, 300 Third St, Cambridge, MA 02142 USA.

NUCLEIC ACID THERAPEUTICS, 2020; 30 (3): 143

Abstract

Hereditary transthyretin-mediated amyloidosis is an inherited, rapidly progressive, life-threatening disease caused by mutated transthyretin (TTR) pro......

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