Dabigatran Acylglucuronide, the Major Metabolite of Dabigatran, Shows a Weaker Anticoagulant Effect than Dabigatran

Kim, JM; Noh, J; Park, JW; Chung, H; Kim, KA; Park, SB; Lee, JS; Park, JY

Park, JY (通讯作者)，Korea Univ, Anam Hosp, Coll Med, Dept Clin Pharmacol & Toxicol, Seoul 02841, South Korea.;Lee, JS (通讯作者)，Korea Univ, Coll Med, Dept Pharmacol, Seoul 02841, South Korea.

PHARMACEUTICS, 2022; 14 (2):

Abstract

Dabigatran (DAB) is an orally administered thrombin inhibitor. Both DAB and its main metabolite dabigatran acylglucuronide (DABG) have established ant......

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