UMI-linked consensus sequencing enables phylogenetic analysis of directed evolution

Zurek, PJ; Knyphausen, P; Neufeld, K; Pushpanath, A; Hollfelder, F

Hollfelder, F (corresponding author), Univ Cambridge, Dept Biochem, Cambridge CB2 1GA, England.

NATURE COMMUNICATIONS, 2020; 11 (1):

Abstract

The success of protein evolution campaigns is strongly dependent on the sequence context in which mutations are introduced, stemming from pervasive no......

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