Does Crizotinib Auto-Inhibit CYP3A in vivo?

Bland, AR; Shrestha, N; Rosengren, RJ; Ashton, JC

Ashton, JC (corresponding author), Univ Otago, Sch Biomed Sci, Dept Pharmacol & Toxicol, 18 Frederick St, Dunedin 9016, Otago, New Zealand.

PHARMACOLOGY, 2020; 105 (11-12): 715

Abstract

Crizotinib is a tyrosine kinase inhibitor used to treat anaplastic lymphoma kinase-positive lung cancer. There is in vitro evidence that crizotinib ma......

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