Plasmid-mediated metronidazole resistance in Clostridioides difficile

Boekhoud, IM; Hornung, BVH; Sevilla, E; Harmanus, C; Bos-Sanders, IMJG; Terveer, EM; Bolea, R; Corver, J; Kuijper, EJ; Smits, WK

Smits, WK (corresponding author), Leiden Univ, Med Ctr, Dept Med Microbiol, Albinusdreef 2,POB 9600, NL-2300 RC Leiden, Netherlands.; Smits, WK (corresponding author), Ctr Microbial Cell Biol, Leiden, Netherlands.; Smits, WK (corresponding author), Netherlands Ctr One Hlth, Leiden, Netherlands.

NATURE COMMUNICATIONS, 2020; 11 (1):

Abstract

Metronidazole was until recently used as a first-line treatment for potentially life-threatening Clostridioides difficile (CD) infection. Although cas......

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