Pharmacokinetics of S-ketamine and R-ketamine and their active metabolites after racemic ketamine or S-ketamine intravenous administration in dogs sedated with medetomidine

Romagnoli, N; Bektas, RN; Kutter, APN; Barbarossa, A; Roncada, P; Hartnack, S; Bettschart-Wolfensberger, R

Barbarossa, A (corresponding author), Univ Bologna, Dept Vet Med Sci, Via Tolara 50, I-40064 Bologna, Italy.

VETERINARY ANAESTHESIA AND ANALGESIA, 2020; 47 (2): 168

Abstract

Objective To assess the differences in the pharmacokinetic profiles of S-ketamine, R-ketamine and their metabolites, S-norketamine and R-norketamine, ......

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