Mechanisms of Polymyxin-Induced Nephrotoxicity

Azad, MAK; Nation, RL; Velkov, T; Li, J

Li, J (reprint author), Monash Univ, Biomed Discovery Inst, Infect & Immun Program, Clayton Campus, Melbourne, Vic, Australia.; Li, J (reprint author), Monash Univ, Dept Microbiol, Clayton Campus, Melbourne, Vic, Australia.

POLYMYXIN ANTIBIOTICS: FROM LABORATORY BENCH TO BEDSIDE, 2019; 1145 (): 305

Abstract

Polymyxin-induced nephrotoxicity is the major dose-limiting factor and can occur in up to 60% of patients after intravenous administration. This chapt......

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