Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole

Surasarang, SH; Keen, JM; Huang, SY; Zhang, F; McGinity, JW; Williams, RO

Williams, RO (reprint author), Univ Texas Austin, Div Pharmaceut, 1 Univ Stn A1920, Austin, TX 78712 USA.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2017; 43 (5): 797

Abstract

The purpose of this study was to enhance the dissolution properties of albendazole (ABZ) by the use of amorphous solid dispersions. Phase diagrams of ......

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