Exploring CYP2J2: lipid mediators, inhibitors and therapeutic implications

Sisignano, M; Steinhilber, D; Parnham, MJ; Geisslinger, G

Sisignano, M (corresponding author), Goethe Univ, Univ Hosp, Inst Clin Pharmacol, Pharmazentrum Frankfurt ZAFES, D-60590 Frankfurt, Germany.; Sisignano, M (corresponding author), Fraunhofer Inst Mol Biol & Appl Ecol IME, Branch Translat Med & Pharmacol TMP, D-60596 Frankfurt, Germany.

DRUG DISCOVERY TODAY, 2020; 25 (9): 1744

Abstract

In contrast to other drug-metabolizing cytochrome P450 (CYP) oxygenases, CYP2J2 shows considerable extrahepatic activity and is responsible for the ol......

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