High affinity interactions of Pb2+ with synaptotagmin I

Katti, S; Her, B; Srivastava, AK; Taylor, AB; Lockless, SW; Igumenova, TI

Igumenova, TI (reprint author), Texas A&M Univ, Dept Biochem & Biophys, 300 Olsen Blvd, College Stn, TX 77843 USA.

METALLOMICS, 2018; 10 (9):

Abstract

Lead (Pb) is a potent neurotoxin that disrupts synaptic neurotransmission. We report that Synaptotagmin I (Sytl), a key regulator of Ca2+-evoked neuro......

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