Liver-specific rescuing of CEACAM1 reverses endothelial and cardiovascular abnormalities in male mice with null deletion of Ceacam1 gene

Russo, L; Muturi, HT; Ghadieh, HE; Wisniewski, AM; Morgan, EE; Quadri, SS; Landesberg, GP; Siragy, HM; Vazquez, G; Scalia, R; Gupta, R; Najjar, SM

Najjar, SM (reprint author), Ohio Univ, Heritage Coll Osteopath Med, Off Grants & Res Irvine Hall,Room 220B,1, Athens, OH 45701 USA.

MOLECULAR METABOLISM, 2018; 9 (): 98

Abstract

Objective: Mice with global null mutation of Ceacam1 (Cc1(-/-)), display impairment of insulin clearance that causes hyperinsulinemia followed by insu......

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