Robust Strategy for Hit-to-Lead Discovery: NMR for SAR

Larda, ST; Ayotte, Y; Denk, MM; Coote, P; Heffron, G; Bendahan, D; Shahout, F; Girard, N; Iddir, M; Bouchard, P; Bilodeau, F; Woo, S; Farmer, LJ; Laplante, SR

Laplante, SR (通讯作者),NMX Res & Solut Inc, Laval, PQ H7V 5B7, Canada.;Laplante, SR (通讯作者),INRS Ctr Armand Frappier Sante Biotechnol, Laval, PQ H7V 1B7, Canada.;Laplante, SR (通讯作者),Harvard Med Sch, Boston, MA 02115 USA.

JOURNAL OF MEDICINAL CHEMISTRY, 2023; ():

Abstract

Establishing robust structure-activity relationships (SARs) is key to successful drug discovery campaigns, yet it often remains elusive due to screeni......

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